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What is Oxycodone Withdrawal?

Oxycodone withdrawal is the physical and mental symptoms you experience after you stop or reduce use.

These unpleasant effects can last about a week during detox.

Oxycodone withdrawal varies for everyone.

It can range from mild to severe depending on how you used it.

Individuals with substance abuse disorders typically have a harder time with oxycodone detox.

You can experience irritability, depression, insomnia, agitation, anxiety. You may have suicidal thoughts and an inability to concentrate.

The Worst Day of Opiate Withdrawal

The worst day for opiate withdrawal can begin a few hours after the last use.

The signs of oxycodone withdrawal vary from person to person.

Many people describe the feeling of flu-like symptoms; fatigue, chills, and diarrhea.

The severity of your symptoms span across a spectrum.

To understand how your oxycodone detox progresses, the Clinical Opiate Withdrawal Scale is a useful tool.

The most common oxycodone withdrawal symptoms include muscle aches and pain, sweating, runny nose, chills, nausea or vomiting, cramping or diarrhea, insomnia, lucid dreams, teary eyes, tremors, restlessness, gooseflesh, heart-pounding, agitation, and skin-crawling.

These symptoms will begin within 8-24 hours after you begin the detoxing process.

Depending on the type of oxycodone, specifically the extended-release tablets, your pain tolerance is diminished.

You may experience the return of severe pain.

Pain can complicate your oxycodone withdrawal.

Understanding Oxycodone Withdrawal

Not everyone will have the same oxycodone withdrawal symptoms. There is no single opiate withdrawal timeline. Nevertheless, the following timeline gives you an idea of what you can expect during detox. Anticipate that your symptoms will progressively get worse and then hit a peak before you find relief.

Day 1 – Oxycodone withdrawal day 1 is the beginning of a week-long process. For many just knowing that journey to detoxing is long and painful can be extremely hard on the mind. Many users experience cravings and become irritable and/or anxious.

Day 2 – The second day of detox is when the real symptoms of oxycodone withdrawal take effect. Your body can tingle. You may experience tremors. Your body is noticing that oxycodone is no longer being supplied. Your brain begins to get frenzied. You also need to make sure you eat well, drink a lot of water, and keep active.

Days 3-5 – The worst day of opiate withdrawal is days 3, 4, and 5. You will go through a myriad of withdrawal symptoms. Often several at one time. Oxycodone withdrawal peaks during this period. Expect during this time to experience tiredness, insomnia, and malaise. You can experience intense episodes of hot and cold flashes. Your legs feel restless and can hurt, this is called restless legs syndrome. Unpleasant bouts of severe diarrhea and stomach pains are often reported at this stage. You may have headaches and migraines, and a complete loss of appetite.

Day 5-7 – After the first week, the feelings of being uncomfortable begin to subside. You will feel more at ease. You can expect to have sleep disturbances for a few weeks. However, this period is mainly associated with strong cravings. Often people going through oxycodone detox will experience anhedonia, which is the inability to feel pleasure. Nevertheless, after time this too will pass.


Opioid withdrawal is rarely dangerous for a healthy adult to do at home. Nevertheless, it can be a difficult and uncomfortable process. The acute symptoms of oxycodone withdrawal typically peak around day three. There are many ways to navigate the negative side effects of oxycodone withdrawal. Today with medical interventions the discomfort of oxycodone withdrawal can be managed. Learning different ways to detox can motivative you to commit to a detox program.

Inpatient Treatment

The benefits of an inpatient oxycodone withdrawal detox can make the difference. With medical support, you can have confidence in your ability to commit from start to finish. The worst day of opiate withdrawal can be hard to handle. With medical intervention every step of the way, the process is more tolerable. Medical supervision is recommended for long term opiate abuse. Several medications can help prevent withdrawal symptoms. Inpatient care allows immediate treatment for any symptoms that develop. Inpatient detox facilities are a great way to get through withdrawal. You are in a safe trigger-free environment to focus on your own needs.

Outpatient Treatment

Once detox is complete, follow up care with outpatient care can help you through the next stage. After the worst days of oxycodone withdrawal, some relapse without continued support. Unfortunately, many people relapse shortly after detoxing. Outpatient care programs allow you to maintain medical support in a less restrictive environment. After you have completed your sessions and medical tests you are free to leave and go home. You can begin to practice the tools you have learned to maintain a sober life. After initial detox, outpatient treatment programs will continue to support your needs. You will gain the tools needed as you continue abstaining from opiates.

Faith-Based Care

Ongoing care is vital to maintain a sober living. For many people having a strong connection to faith is a key part of sober living. You learn spiritual coping tools that help keep you mindful. Learning from others’ mistakes and experiences can help you to maintain your resolve. Staying strong so you never have to face the worst days of oxycodone withdrawal again. Strong faith is an important part of keeping the commitment to a sober life.

Executive Treatment

Executive treatment offers therapy that allows executives to work through their recovery. This level of care minimizes the impact on your professional and personal life. The goal is to handle your treatment from start to finish. This allows you to focus on recovery. The executive level of care handles insurance information and coordinate travel arrangements. It also provides scheduling detox if this is a necessary step and coordinate aftercare.

Payment Information

Do you want treatment but are worried about how you can pay for it? We have a team of financial professionals who provide free insurance verification. We will work with you to determine how to move forward with the treatment in a way that works for you and your financial situation.

How to Get Help

Are you struggling with oxycodone addiction?

Do you fear the worst day of oxycodone withdrawal?

If you answered yes, then a medical detoxing program can be the answer.

At Resurgence Behavioral Health we understand how difficult the road to detox is.

Doing it alone can seem impossible. Supportive care for detox is essential for positive long-term outcomes.

Call Resurgence Behavioral Health at (855) 458-0050 to schedule your consultation.